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Learn More About The Process Of PRP Treatment Blood cells that form the bone marrow is referred as platelets and they’re containing packets of protein that’s responsible for blood clotting and wound healing. The moment that the platelets are released into the bloodstream from the marrow, they have a circulating lifespan of 7 to 10 days. Whenever there is an acute injury, you can be sure that there is going to be the accumulation of platelets at site. There is sequence of events that take place with the formation of cloth as well as the released of growth factors. These said growth factors will attract different blood cells in the said area. With regards to the healing process, some other growth factors and cells help with the healing process. Most of the time, addition of human thrombin and calcium chloride has been considered to be able to stimulate the release of these growth factors. There’ve been several counts of hypersensitivity reactions to small number of patients while bovine thrombin are used. PRP or Platelet Rich Plasma is actually a concentrate of the entire body that contains a minimum of 1 million platelets per 6cc’s. Preferably, platelet concentration that ranges in 3 to 5 million is ideal since higher concentration of platelets indicate that there are more growth factors and thus, faster healing.
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Among early papers that describe the use of PRP was established in American Journal of Sports Medicine. Researchers presented non randomized study of 20 patients with chronic lateral epicondylitis or tennis elbow. For the next 2 months, the patients were closely monitored after receiving PRP treatment and there is around 60 percent improvement PRP treated group than the 16 percent in the control group.
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This said treatment has been studied too for Achilles tendon problems that produced mixed results. Dutch study was published in American Medical Association back in 2010 that involves 54 patients who showed no statistical difference between the groups that were treated with exercise and saline and groups receiving PRP treatments. On the other hand, there’s been some criticism with regards to the study design and other studies reporting some positive results with PRP in treating Achilles tendonitis. Other conditions for which PRP treatment was known to be used are patellar tendonitis, rotator cuff tendonitis of shoulder, gluteus medius tendonitis of hip, plantar fasciitis and even osteoarthritis. When the PRP is applied after needle tenotomy or a procedure to which a small incision is made to part damaged tendon by ultrasound guidance with a small needle, this create an acute injury. This acute injury is actually what stimulating acute inflammatory response, that will then cause the release of platelet’s growth as well as healing factors.

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